Characterization of Spray Dried Extract Katuk (Sauropus androgynus)

نویسندگان

چکیده

Katuk (Sauropus androgynus) leaves have been traditionally used in Indonesia for increasing human breast milk production. In the previous research, katuk high moisture content, therefore extract were being prepared as spray dried S. androgynus extract. The freeze extracted with ultrasonic assisted extraction method using ethanol 80% a solvent. Then, was drying maltodextrin aid. To improve physical characteristics of this extract, it mixed mannitol, lactose, and crospovidone into powder. results showed better characteristics, especially on content flow properties powders. Metabolic profiles all samples analysed by thin layer chromatography (TLC) densitometry method, while dissolved suitable solvent then spotted GF254 plate developed mixture n-butanol:acetic acid:water (60:22:1.2). Based TLC profiles, there are three different spots can be seen clearly at 366 nm chromatogram leaves, There is one spot (S3) Rf 0.80 which stable chemical compound that not affected factors entire process powder formulations from extraction, drying, to formulation.

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ژورنال

عنوان ژورنال: INDONESIAN JOURNAL OF PHARMACY

سال: 2022

ISSN: ['2338-9427', '2338-9486']

DOI: https://doi.org/10.22146/ijp.4443